Projects

Die Reparatur von Leistenbrüchen gehört zu den häufigsten chirurgischen Eingriffen weltweit (> 20 Millionen/Jahr). Rezidive und anhaltende postoperative Schmerzen sind die beiden Hauptprobleme nach einer Leistenhernienreparatur. Beide werden durch das implantierte Netzmaterial beeinflusst. Absorbierbare Kollagenmatrizen, so genannte biologische Netze, sollen einen postoperativen Gewebeumbau der Bauchwand bewirken - ohne die Notwendigkeit eines lebenslangen synthetischen Implantats. Um die ...

The study has the aim to show that using no tamponade dressing after haemorrhoidectomy ist not inferior to the use of a tamponade regarding postoperative bleeding.

Many approaches to the surgical treatment of OF-P have been tried, but no one method has stood out as particularly successful. The placement of three implants, including implants that could minimise motion in the sacroiliac joint through early fixation and long-term fusion of the sacroiliac joint, can prevent micromotion in the fracture and thereby improve the clinical outcome of OF-Ps.

The iFuse-3D implant was shown to be safe and effective for chronic sacroiliac pain in non-osteoporotic patients. ...

With over 15,000 implantations worldwide to date, the MitraClip procedure has established itself as a treatment for patients with mitral valve insufficiency. It is the only minimally invasive, transcatheter mitral valve therapy available. A standardised, multimodal approach ("MitraScore") has been developed for the assessment of residual mitral valve regurgitation after MitraClip implantation. It has been shown that a low MitraScore is associated with a better long-term outcome after MitraClip ...

The emotion Egg, or "eEgg" for short, is a sample series of a device for testing a new pain measurement method that is not yet on the market. The aim is to investigate whether the trial device and the eEgg method (eEgg plus software) are suitable for supporting, improving or even replacing the communication between doctor and patient, which still takes place via the numerical rating scale (NRS) and the pain diary. Issues of acceptability in comparison to the pain diary and the NRS are to be ...

The basic immunizations (first and second vaccination) were performed from January to June 2021 using the m-RNA vaccine BNT162b2 (BioNTech/Pfizer, B)9 and the vector-based vaccine ChAdOx1-S (AstraZeneca, A). BNT162b2 was used to boost vaccine all study population. The time interval between the basic immunisation and the boost vaccination varied.

Four vaccine-groups could be distinguished:

Group 1 received BNT162b2 with the second vaccination 3 weeks after the first vaccination.

Vaccinees of groups ...